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Diacylglycerol Kinase Alpha (DGKA) Antibody
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Catalogue No: abx033889
Price:
US$326.25
(Size: 80 µl)
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Upon cell stimulation, the kinase DGKA converts the second messenger diacylglycerol into phophatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. DGKA is stimulated by calcium and phosphatidylserine, and is phosphorylated by protein kinase C. Tissue expression is in lymphocytes and oligodengroglial cells. DGKA contains 2 zinc-dependent phorbol-ester and DAG binding domains, and 2 EF-hand calcium binding domains.
Research Articles on Diacylglycerol Kinase Alpha (DGKA)
| Target | Diacylglycerol Kinase Alpha (DGKA) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 598-628 amino acids from the C-terminal region of human DGKA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23743 (UniProt, ExPASy) |
| UniProt Secondary AC | O75481, O75482, O75483, O95217, Q3ZE25, Q8IZ56, Q8N5Q2 |
| UniProt Entry Name | DGKA_HUMAN |
| KEGG | hsa:1606 |
| String | 9606.ENSP00000328405 |
| Molecular Weight | Calculated MW: 82.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |