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24-Dehydrocholesterol Reductase (DHCR24) Antibody
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Catalogue No: abx004137
Price:
US$203.00
(Size: 20 µl)
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DHCR24 Antibody is a Rabbit Polyclonal antibody against DHCR24. This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Research Articles on 24-Dehydrocholesterol Reductase (DHCR24)
| Target | 24-Dehydrocholesterol Reductase (DHCR24) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 227-516 of human DHCR24. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15392 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z817, D3DQ51, Q9HBA8 |
| UniProt Entry Name | DHC24_HUMAN |
| Gene Symbol | DHCR24 |
| GeneID | 1718 |
| NCBI Accession | NP_055577.1 |
| KEGG | hsa:1718 |
| String | 9606.ENSP00000360316 |
| Molecular Weight | Calculated MW: 60 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.27 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |