Dihydrofolate Reductase (DHFR) Antibody

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Catalogue No: abx001351
Price: US$348.00
(Size: 60 µl)

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Dihydrofolate Reductase (DHFR) Antibody

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Datasheet SDS
DHFR Antibody is a Rabbit Polyclonal antibody against DHFR. Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008].

Target Dihydrofolate Reductase (DHFR)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications IF/ICC
Host Rabbit
Recommended dilutions IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein corresponding to human DHFR
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P00374 (UniProt, ExPASy)
UniProt Secondary AC B4DDD2, Q14130, Q6IRW8
UniProt Entry Name DYR_HUMAN
Gene Symbol DHFR
GeneID 1719
NCBI Accession NP_000782.1
KEGG hsa:1719
String 9606.ENSP00000396308
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Dihydrofolate Reductase (DHFR)

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