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Dihydrofolate Reductase (DHFR) Antibody
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Catalogue No: abx001351
Price:
US$203.00
(Size: 20 µl)
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DHFR Antibody is a Rabbit Polyclonal antibody against DHFR. Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008].
Research Articles on Dihydrofolate Reductase (DHFR)
| Target | Dihydrofolate Reductase (DHFR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human DHFR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P00374 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DDD2, Q14130, Q6IRW8 |
| UniProt Entry Name | DYR_HUMAN |
| Gene Symbol | DHFR |
| GeneID | 1719 |
| NCBI Accession | NP_000782.1 |
| KEGG | hsa:1719 |
| String | 9606.ENSP00000396308 |
| Molecular Weight | Calculated MW: 21 kDa Observed MW: 19 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |