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Desert Hedgehog Protein (DHH) Antibody
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Catalogue No: abx030820
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
Research Articles on Desert Hedgehog Protein (DHH)
| Target | Desert Hedgehog Protein (DHH) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 195-223 amino acids from the Central region of human DHH. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43323 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15794 |
| UniProt Entry Name | DHH_HUMAN |
| Gene Symbol | DHH |
| GeneID | 50846 |
| OMIM | 233420 |
| HGNC | 2865 |
| KEGG | hsa:50846 |
| Ensembl | ENSG00000139549 |
| String | 9606.ENSP00000266991 |
| Molecular Weight | Calculated MW: 43.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse DHH. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |