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Diaphanous Homolog 3 (Drosophila) (DIAPH3) Antibody
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Catalogue No: abx028919
Price:
US$326.25
(Size: 80 µl)
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DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).
Research Articles on Diaphanous Homolog 3 (Drosophila) (DIAPH3)
| Target | Diaphanous Homolog 3 (Drosophila) (DIAPH3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NSV4 (UniProt, ExPASy) |
| UniProt Entry Name | DIAP3_HUMAN |
| Gene Symbol | DIAPH3 |
| String | 9606.ENSP00000383178 |
| Molecular Weight | Calculated MW: 137 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |