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Dimethylglycine Dehydrogenase (DMGDH) Antibody
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Catalogue No: abx029935
Price:
US$290.00
(Size: 80 µl)
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This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.
Research Articles on Dimethylglycine Dehydrogenase (DMGDH)
| Target | Dimethylglycine Dehydrogenase (DMGDH) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 836-864 amino acids from the C-terminal region of human DMGDH. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UI17 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RBN0, B4E1J9 |
| UniProt Entry Name | M2GD_HUMAN |
| Gene Symbol | DMGDH |
| String | 9606.ENSP00000255189 |
| Molecular Weight | Calculated MW: 96.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |