Dynamin-1 (DNM1) Antibody

DNM1 Antibody is a Rabbit Polyclonal antibody against DNM1. This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Target	Dynamin-1 (DNM1)
Clonality	Polyclonal
Reactivity	Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 400-490 of human DNM1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q05193 (UniProt, ExPASy)
UniProt Secondary AC	A6NLM6, Q5SYX0, Q5SYX2, Q6P3T6, Q86VD2
UniProt Entry Name	DYN1_HUMAN
Gene Symbol	DNM1
GeneID	1759
NCBI Accession	NP_004399.2
KEGG	hsa:1759
String	9606.ENSP00000362014
Molecular Weight	Calculated MW: 97 kDa Observed MW: 110 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dynamin-1 (DNM1)

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