DNA Methyltransferase 3 Alpha (DNMT3A) Antibody

DNA Methyltransferase 3 Alpha (DNMT3A) Antibody is a Rabbit Polyclonal antibody for the detection of DNMT3A.

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Target	DNA Methyltransferase 3 Alpha (DNMT3A)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, IHC
Host	Rabbit
Recommended dilutions	IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	DNA (cytosine-5-)-methyltransferase 3 alpha
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q9Y6K1 (UniProt, ExPASy)
UniProt Secondary AC	E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9
UniProt Entry Name	DNM3A_HUMAN
Gene Symbol	DNMT3A
GeneID	1788
OMIM	602769
HGNC	2978
Ensembl	ENSG00000119772
String	9606.ENSP00000264709
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on DNA Methyltransferase 3 Alpha (DNMT3A)

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