DNA Methyltransferase 3 Like (Dnmt3L) Antibody

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Catalogue No: abx025810
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.

Target DNA Methyltransferase 3 Like (Dnmt3L)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9CWR8 (UniProt, ExPASy)
UniProt Entry Name DNM3L_MOUSE
String 10090.ENSMUSP00000121562
Molecular Weight Calculated MW: 48 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat Dnmt3l.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on DNA Methyltransferase 3 Like (Dnmt3L)


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