+44 (0) 1223 755950
+1 832 327 7413
Terminal Deoxynucleotidyltransferase (DNTT) Antibody
REQUEST MORE INFO
Catalogue No: abx004776
Price:
US$203.00
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
DNTT Antibody is a Rabbit Polyclonal antibody against DNTT. This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Research Articles on Terminal Deoxynucleotidyltransferase (DNTT)
| Target | Terminal Deoxynucleotidyltransferase (DNTT) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 260-509 of human TdT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04053 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53FH1, Q5W103, Q96E50 |
| UniProt Entry Name | TDT_HUMAN |
| Gene Symbol | DNTT |
| GeneID | 1791 |
| NCBI Accession | NP_004079.3 |
| KEGG | hsa:1791 |
| String | 9606.ENSP00000360216 |
| Molecular Weight | Calculated MW: 59 kDa Observed MW: 55/58 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |