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Protein Dok-7 (DOK7) Antibody
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Catalogue No: abx027473
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Research Articles on Protein Dok-7 (DOK7)
| Target | Protein Dok-7 (DOK7) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q18PE1 (UniProt, ExPASy) |
| UniProt Secondary AC | A2A499, A2RRD4, E9PB56, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1 |
| UniProt Entry Name | DOK7_HUMAN |
| KEGG | hsa:285489 |
| String | 9606.ENSP00000344432 |
| Molecular Weight | Calculated MW: 53.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |