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Dihydropyrimidine Dehydrogenase (DPYD) Antibody
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Catalogue No: abx001364
Price:
US$203.00
(Size: 20 µl)
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DPYD Antibody is a Rabbit Polyclonal antibody against DPYD. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Dihydropyrimidine Dehydrogenase (DPYD)
| Target | Dihydropyrimidine Dehydrogenase (DPYD) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12882 (UniProt, ExPASy) |
| UniProt Entry Name | DPYD_HUMAN |
| Gene Symbol | DPYD |
| GeneID | 1806 |
| NCBI Accession | NP_000101.2 |
| KEGG | hsa:1806 |
| String | 9606.ENSP00000359211 |
| Molecular Weight | Calculated MW: 111 kDa Observed MW: 112 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |