DRG11-Responsive Axonal Guidance And Outgrowth of Neurite (DRAGON) Antibody

Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.

Target	DRG11-Responsive Axonal Guidance And Outgrowth of Neurite (DRAGON)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 278-309 amino acids from the Central region of human DRAGON (RGMB).
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q6NW40 (UniProt, ExPASy)
UniProt Secondary AC	D6R9A0, Q8NC92
UniProt Entry Name	RGMB_HUMAN
KEGG	hsa:285704
String	9606.ENSP00000308219
Molecular Weight	Calculated MW: 47.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DRG11-Responsive Axonal Guidance And Outgrowth of Neurite (DRAGON)

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