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Down Syndrome Critical Region Protein 3 (DSCR3) Antibody
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Catalogue No: abx032797
Price:
US$326.25
(Size: 80 µl)
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The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
Research Articles on Down Syndrome Critical Region Protein 3 (DSCR3)
| Target | Down Syndrome Critical Region Protein 3 (DSCR3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DSCR3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14972 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6T8, B7Z6B1, D3DSH4, Q2TAY6 |
| UniProt Entry Name | VP26C_HUMAN |
| Gene Symbol | VPS26C |
| KEGG | hsa:10311 |
| String | 9606.ENSP00000311399 |
| Molecular Weight | Calculated MW: 33 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |