Dystrobrevin Binding Protein 1 (Dtnbp1) Antibody

Dtnp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this protein are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.

Target	Dystrobrevin Binding Protein 1 (Dtnbp1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human Dtnbp1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q91WZ8 (UniProt, ExPASy)
UniProt Secondary AC	Q3TWK1, Q6WXQ1, Q80ZN4, Q9CY43
UniProt Entry Name	DTBP1_MOUSE
NCBI Accession	NP_080048.2
KEGG	mmu:94245
String	10090.ENSMUSP00000072170
Molecular Weight	Calculated MW: 39.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dystrobrevin Binding Protein 1 (Dtnbp1)

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