Dystrobrevin Binding Protein 1 (DTNBP1) Antibody

DTNBP1 Antibody is a Rabbit Polyclonal antibody against DTNBP1. This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Target	Dystrobrevin Binding Protein 1 (DTNBP1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human DTNBP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96EV8 (UniProt, ExPASy)
UniProt Secondary AC	A8K3V3, Q5THY3, Q5THY4, Q96NV2, Q9H0U2, Q9H3J5
UniProt Entry Name	DTBP1_HUMAN
Gene Symbol	DTNBP1
GeneID	84062
NCBI Accession	NP_115498.2
KEGG	hsa:84062
String	9606.ENSP00000341680
Molecular Weight	Calculated MW: 39 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dystrobrevin Binding Protein 1 (DTNBP1)

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