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Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1) Antibody
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Catalogue No: abx026731
Price:
US$326.25
(Size: 80 µl)
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DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Research Articles on Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1)
| Target | Segment Polarity Protein Dishevelled Homolog DVL-1 (DVL1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25, IF/ICC: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14640 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5TA33, Q5TA35 |
| UniProt Entry Name | DVL1_HUMAN |
| Gene Symbol | DVL1 |
| KEGG | hsa:1855 |
| String | 9606.ENSP00000368169 |
| Molecular Weight | Calculated MW: 75.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat DVL1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |