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Dynactin Subunit 4 (DCTN4) Antibody
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Catalogue No: abx015835
Price:
US$427.75
(Size: 100 µl)
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Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping.Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.
Research Articles on Dynactin Subunit 4 (DCTN4)
| Target | Dynactin Subunit 4 (DCTN4) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UJW0 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KWW0, D3DQH0, E5RGT5, Q8TAN8 |
| UniProt Entry Name | DCTN4_HUMAN |
| Gene Symbol | DCTN4 |
| GeneID | 51164 |
| OMIM | 614758 |
| HGNC | 15518 |
| Ensembl | ENSG00000132912 |
| String | 9606.ENSP00000414906 |
| Molecular Weight | 52.3 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |