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Dynein Light Chain Tctex-Type 1 (DYNLT1) Antibody
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Catalogue No: abx003064
Price:
US$203.00
(Size: 20 µl)
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DYNLT1 Antibody is a Rabbit Polyclonal antibody against DYNLT1. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Dynein Light Chain Tctex-Type 1 (DYNLT1)
| Target | Dynein Light Chain Tctex-Type 1 (DYNLT1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human DYNLT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P63172 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15763, Q5VTU4 |
| UniProt Entry Name | DYLT1_HUMAN |
| Gene Symbol | DYNLT1 |
| GeneID | 6993 |
| NCBI Accession | NP_006510.1 |
| KEGG | hsa:6993 |
| String | 9606.ENSP00000356056 |
| Molecular Weight | Calculated MW: 12 kDa Observed MW: 13 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |