E2F Transcription Factor 6 (E2F6) Antibody

E2F6 Antibody is a Rabbit Polyclonal antibody against E2F6. This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.

Target	E2F Transcription Factor 6 (E2F6)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IP: 0.5-4 µg/200-400 µg whole cell extracts, ChIP: 5 µg/10-15 µg Chromatin. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human E2F6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75461 (UniProt, ExPASy)
UniProt Secondary AC	A8K2Z8, G5E936, O60544, Q53QY9, Q6Q9Z6, Q7Z2H6
UniProt Entry Name	E2F6_HUMAN
Gene Symbol	E2F6
GeneID	1876
NCBI Accession	NP_937987.2
KEGG	hsa:1876
String	9606.ENSP00000370936
Molecular Weight	Calculated MW: 32 kDa Observed MW: 36 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on E2F Transcription Factor 6 (E2F6)

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