Tumor Necrosis Factor Receptor Superfamily Member 27 (EDA2R) Antibody

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq].

Target	Tumor Necrosis Factor Receptor Superfamily Member 27 (EDA2R)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 267-297 amino acids from the C-terminal region of human EDA2R.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9HAV5 (UniProt, ExPASy)
UniProt Secondary AC	Q5VYX9, Q5VYY0, Q6UWM2, Q8IZA6
UniProt Entry Name	TNR27_HUMAN
Gene Symbol	EDA2R
String	9606.ENSP00000379365
Molecular Weight	Calculated MW: 32.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 27 (EDA2R)

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