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Endothelin Receptor Type B (EDNRB) Antibody
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Catalogue No: abx032985
Price:
US$290.00
(Size: 80 µl)
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EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
Research Articles on Endothelin Receptor Type B (EDNRB)
| Target | Endothelin Receptor Type B (EDNRB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human EDN_. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P24530 (UniProt, ExPASy) |
| UniProt Entry Name | EDNRB_HUMAN |
| NCBI Accession | NP_000106.1 NP_001116131.1 NP_001188326.1 NP_003982.1 |
| KEGG | hsa:1910 |
| String | 9606.ENSP00000366416 |
| Molecular Weight | Calculated MW: 49.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat, Cow, Pig and Horse EDNRB. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |