Ephrin Type-B Receptor 6 (EhpB6) Antibody

EhpB6: EPH receptor B6.Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins.The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Target	Ephrin Type-B Receptor 6 (EhpB6)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of EphB6 (aa601-750) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15197 (UniProt, ExPASy)
UniProt Secondary AC	A4D2I7, A8CDT5, D3DXD3, Q2TB23, Q2TB24
UniProt Entry Name	EPHB6_HUMAN
Gene Symbol	EPHB6
GeneID	2051
OMIM	602757
HGNC	3396
KEGG	hsa:2051
Ensembl	ENSG00000106123
String	9606.ENSP00000481994
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ephrin Type-B Receptor 6 (EhpB6)

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