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Eukaryotic Translation Initiation Factor 3 Subunit L (EIF3L) Antibody
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Catalogue No: abx031228
Price:
US$326.25
(Size: 80 µl)
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Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Research Articles on Eukaryotic Translation Initiation Factor 3 Subunit L (EIF3L)
| Target | Eukaryotic Translation Initiation Factor 3 Subunit L (EIF3L) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human EIF3L. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y262 (UniProt, ExPASy) |
| UniProt Entry Name | EIF3L_HUMAN |
| Gene Symbol | EIF3L |
| String | 9606.ENSP00000485663 |
| Molecular Weight | Calculated MW: 66.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Cow, Chicken and Xenopus EIF3L. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |