Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) Antibody

EIF4A1 Antibody is a Rabbit Polyclonal antibody against EIF4A1. EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Target	Eukaryotic Translation Initiation Factor 4A1 (EIF4A1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human eIF4A1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P60842 (UniProt, ExPASy)
UniProt Secondary AC	B2R6L8, D3DTP9, J3QLC4, P04765, Q5U018, Q61516
UniProt Entry Name	IF4A1_HUMAN
Gene Symbol	EIF4A1
GeneID	1973
NCBI Accession	NP_001407.1
KEGG	hsa:1973
String	9606.ENSP00000293831
Molecular Weight	Calculated MW: 46 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Eukaryotic Translation Initiation Factor 4A1 (EIF4A1)

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