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Eukaryotic Initiation Factor 4A-II (EIF4A2) Antibody
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Catalogue No: abx034268
Price:
US$326.25
(Size: 80 µl)
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Eukaryotic initiation factor 4A plays an important role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins. Two highly homologous forms of functional EIF4A genes, Eif4a1 and Eif4a2, have been isolated in mice; yeast cells also possess 2 EIF4A genes, TIF1 and TIF2. The murine Eif4a and yeast TIF genes appear to belong to a DEAD-box gene family, whose members exhibit extensive amino acid similarity and contain the asp-glu-ala-asp (DEAD) sequence. DEAD-box genes have been identified in species ranging from E-coli to humans. Their function appears to be related to transcriptional/translational regulation (referenced from OMIM).
Research Articles on Eukaryotic Initiation Factor 4A-II (EIF4A2)
| Target | Eukaryotic Initiation Factor 4A-II (EIF4A2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/4000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 333-360 amino acids from the C-terminal region of human EIF4A2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14240 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DNU9, Q53XJ6, Q96B90, Q96EA8 |
| UniProt Entry Name | IF4A2_HUMAN |
| KEGG | hsa:1974 |
| String | 9606.ENSP00000326381 |
| Molecular Weight | Calculated MW: 46.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Monkey EIF4A2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |