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Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibody
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Catalogue No: abx031230
Price:
US$326.25
(Size: 80 µl)
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EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Research Articles on Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1)
| Target | Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 48-77 amino acids from human EIF4EBP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13541 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R502, D3DSW8, Q6IBN3 |
| UniProt Entry Name | 4EBP1_HUMAN |
| KEGG | hsa:1978 |
| String | 9606.ENSP00000340691 |
| Molecular Weight | Calculated MW: 12.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow EIF4EBP1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |