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Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibody
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Catalogue No: abx001160
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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EIF4EBP1 Antibody is a Rabbit Polyclonal antibody against EIF4EBP1. This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Research Articles on Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1)
| Target | Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human EIF4EBP1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13541 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R502, D3DSW8, Q6IBN3 |
| UniProt Entry Name | 4EBP1_HUMAN |
| Gene Symbol | EIF4EBP1 |
| GeneID | 1978 |
| NCBI Accession | NP_004086.1 |
| KEGG | hsa:1978 |
| String | 9606.ENSP00000340691 |
| Molecular Weight | Calculated MW: 12 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
