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Eukaryotic Translation Initiation Factor 5A-1 (EIF5A) Antibody
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Catalogue No: abx215126
Price:
US$406.00
(Size: 100 µg)
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Eukaryotic Translation Initiation Factor 5A-1 (EIF5A) Antibody is a Rabbit Polyclonal antibody for the detection of EIF5A. mRNA-binding protein involved in translation elongation.Has an important function at the level of Mrna turnover, probably acting downstream of decapping.Involved in actin dynamics and cell cycle progression,mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.With syntenin SDCBP,functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis.Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival.May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
Research Articles on Eukaryotic Translation Initiation Factor 5A-1 (EIF5A)
| Target | Eukaryotic Translation Initiation Factor 5A-1 (EIF5A) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | eukaryotic translation initiation factor 5A |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P63241 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K9A0, D3DTP2, P10159, Q16182, Q7L7L3, Q7Z4L1, Q9D0G2 |
| UniProt Entry Name | IF5A1_HUMAN |
| Gene Symbol | EIF5A |
| GeneID | 1984 |
| OMIM | 600187 |
| HGNC | 3300 |
| KEGG | hsa:1984 |
| Ensembl | ENSG00000132507 |
| String | 9606.ENSP00000336702 |
| Molecular Weight | Observed MW: 17 kDa/34 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |