ELAV Like RNA Binding Protein 3 (ELAVL3) Antibody

A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target	ELAV Like RNA Binding Protein 3 (ELAVL3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14576 (UniProt, ExPASy)
UniProt Secondary AC	Q16135, Q96CL8, Q96QS9
UniProt Entry Name	ELAV3_HUMAN
KEGG	hsa:1995
String	9606.ENSP00000352162
Molecular Weight	Calculated MW: 39.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse ELAVL3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ELAV Like RNA Binding Protein 3 (ELAVL3)

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