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Empty Spiracles Homeobox 2 (EMX2) Antibody
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Catalogue No: abx032553
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.
Research Articles on Empty Spiracles Homeobox 2 (EMX2)
| Target | Empty Spiracles Homeobox 2 (EMX2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 111-138 amino acids from the Central region of human EMX2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q04743 (UniProt, ExPASy) |
| UniProt Secondary AC | G3V305, Q96NN8, Q9BQF4 |
| UniProt Entry Name | EMX2_HUMAN |
| KEGG | hsa:2018 |
| String | 9606.ENSP00000450962 |
| Molecular Weight | Calculated MW: 28.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow EMX2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |