Equilibrative Nucleoside Transporter 1 (ENT1) Antibody

ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.

Target	Equilibrative Nucleoside Transporter 1 (ENT1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/500, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human ENT1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99808 (UniProt, ExPASy)
UniProt Secondary AC	B3KQV7, B3KQY5, Q5T9W9, Q9UJY2
Gene Symbol	ENT1
NCBI Accession	NP_001071642.1 NP_001071643.1 NP_001071644.1 NP_001071645.1 NP_004946.1
KEGG	hsa:2030
Molecular Weight	Calculated MW: 50.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat SLC29A1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Equilibrative Nucleoside Transporter 1 (ENT1)

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