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Equilibrative Nucleoside Transporter 1 (ENT1) Antibody
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Catalogue No: abx025959
Price:
US$326.25
(Size: 80 µl)
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ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
Research Articles on Equilibrative Nucleoside Transporter 1 (ENT1)
| Target | Equilibrative Nucleoside Transporter 1 (ENT1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/500, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human ENT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99808 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KQV7, B3KQY5, Q5T9W9, Q9UJY2 |
| Gene Symbol | ENT1 |
| NCBI Accession | NP_001071642.1 NP_001071643.1 NP_001071644.1 NP_001071645.1 NP_004946.1 |
| KEGG | hsa:2030 |
| Molecular Weight | Calculated MW: 50.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat SLC29A1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |