EPH Receptor A1 (EphA1) Antibody

EPH receptor A1 (EphA1), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.

Target	EPH Receptor A1 (EphA1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of EphA1 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P21709 (UniProt, ExPASy)
UniProt Secondary AC	A1L3V3, B5A966, B5A967, Q15405
UniProt Entry Name	EPHA1_HUMAN
Gene Symbol	EPHA1
GeneID	2041
OMIM	179610
HGNC	3385
KEGG	hsa:2041
Ensembl	ENSG00000146904
String	9606.ENSP00000275815
Enzyme Commission Number	EC 2.7.10.1
Molecular Weight	108 kDa
Buffer	PBS, containing 0.03% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on EPH Receptor A1 (EphA1)

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