Ephrin Type B Receptor 3 (EphB3) Antibody

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Target	Ephrin Type B Receptor 3 (EphB3)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of EphB3 (aa39-212) expressed in E. coli.
Isotype	IgG2a
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P54753 (UniProt, ExPASy)
UniProt Secondary AC	Q7Z740
UniProt Entry Name	EPHB3_HUMAN
Gene Symbol	EPHB3
GeneID	2049
OMIM	601839
HGNC	3394
KEGG	hsa:2049
Ensembl	ENSG00000182580
String	9606.ENSP00000332118
Enzyme Commission Number	EC 2.7.10.1
Molecular Weight	110 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ephrin Type B Receptor 3 (EphB3)

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