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EPH Receptor A4 (EPHB4) Antibody
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Catalogue No: abx010727
Price:
US$420.50
(Size: 100 µl)
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Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
Research Articles on EPH Receptor A4 (EPHB4)
| Target | EPH Receptor A4 (EPHB4) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of EphB4 expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54760 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A970, B5A971, B5A972, Q7Z635, Q9BTA5, Q9BXP0 |
| UniProt Entry Name | EPHB4_HUMAN |
| Gene Symbol | EPHB4 |
| GeneID | 2050 |
| OMIM | 600011 |
| HGNC | 3395 |
| KEGG | hsa:2050 |
| Ensembl | ENSG00000196411 |
| String | 9606.ENSP00000350896 |
| Enzyme Commission Number | EC 2.7.10.1 EC 2.7.1.112 |
| Molecular Weight | 108 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |