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EPH Receptor A4 (EPHB4) Antibody
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Catalogue No: abx002341
Price:
US$203.00
(Size: 20 µl)
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EPHB4 Antibody is a Rabbit Polyclonal antibody against EPHB4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
Research Articles on EPH Receptor A4 (EPHB4)
| Target | EPH Receptor A4 (EPHB4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 300-540 of human EPHB4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9ULX5 (UniProt, ExPASy) |
| UniProt Secondary AC | O60633, Q7Z5V9 |
| UniProt Entry Name | RN112_HUMAN |
| Gene Symbol | RNF112 |
| GeneID | 2050 |
| NCBI Accession | NP_004435.3 |
| String | 9606.ENSP00000454919 |
| Molecular Weight | Calculated MW: 108 kDa Observed MW: 108 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |