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Ephrin Type-B Receptor 6 (EphB6) Antibody
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Catalogue No: abx015742
Price:
US$420.50
(Size: 100 µl)
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EPH receptor B6 (EphB6), with 1006-amino acid protein (~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family.Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development.EphB6 is expressed both in a variety of embryonic and adult tissues.EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive.EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
Research Articles on Ephrin Type-B Receptor 6 (EphB6)
| Target | Ephrin Type-B Receptor 6 (EphB6) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of EphB6 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15197 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D2I7, A8CDT5, D3DXD3, Q2TB23, Q2TB24 |
| UniProt Entry Name | EPHB6_HUMAN |
| Gene Symbol | EPHB6 |
| GeneID | 2051 |
| OMIM | 602757 |
| HGNC | 3396 |
| KEGG | hsa:2051 |
| Ensembl | ENSG00000106123 |
| String | 9606.ENSP00000481994 |
| Buffer | PBS, containing 0.03% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |