+44 (0) 1223 755950
+1 832 327 7413
Ephrin Type-B Receptor 6 (EphB6) Antibody
REQUEST MORE INFO
Catalogue No: abx033538
Price:
US$290.00
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
Research Articles on Ephrin Type-B Receptor 6 (EphB6)
| Target | Ephrin Type-B Receptor 6 (EphB6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human EphB6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15197 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D2I7, A8CDT5, D3DXD3, Q2TB23, Q2TB24 |
| UniProt Entry Name | EPHB6_HUMAN |
| Gene Symbol | EPHB6 |
| KEGG | hsa:2051 |
| String | 9606.ENSP00000481994 |
| Molecular Weight | Calculated MW: 111 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat EPHB6. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |