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Epidermal Growth Factor Receptor (EGFR) Antibody
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Catalogue No: abx240014
Price:
US$406.00
(Size: 100 µg)
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Epidermal Growth Factor Receptor (EGFR) Antibody is a Mouse Monoclonal antibody for the detection of EGFR. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Research Articles on Epidermal Growth Factor Receptor (EGFR)
| Target | Epidermal Growth Factor Receptor (EGFR) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | WB: 1/2000 - 1/10000, IHC: 1/100 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | epidermal growth factor receptor |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P00533 (UniProt, ExPASy) |
| UniProt Entry Name | EGFR_HUMAN |
| Gene Symbol | EGFR |
| GeneID | 1956 |
| OMIM | 131550 |
| HGNC | 3236 |
| KEGG | hsa:1956 |
| Ensembl | ENSG00000146648 |
| String | 9606.ENSP00000275493 |
| Molecular Weight | Observed MW: 140-160 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |