Epithelial Cell Adhesion Molecule (EPCAM) Antibody

Epithelial Cell Adhesion Molecule (EPCAM) Antibody is a Mouse Monoclonal antibody for the detection of EPCAM.

Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. (PMID: 20837599; 19249674; 21576002; 22647938)

Target	Epithelial Cell Adhesion Molecule (EPCAM)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	WB: 1/1000 - 1/10000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	epithelial cell adhesion molecule
Isotype	IgG1
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P16422 (UniProt, ExPASy)
UniProt Secondary AC	P18180, Q6FG26, Q6FG49, Q96C47, Q9UCD0
UniProt Entry Name	EPCAM_HUMAN
Gene Symbol	EPCAM
GeneID	4072
OMIM	185535
HGNC	11529
KEGG	hsa:4072
Ensembl	ENSG00000119888
String	9606.ENSP00000263735
Molecular Weight	Observed MW: 36 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Epithelial Cell Adhesion Molecule (EPCAM)

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