Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody

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Catalogue No: abx033544
Price: US$326.25
(Size: 80 µl)

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Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody
Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2) Antibody

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Datasheet SDS
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An Interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.

Target Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 21-52 amino acids from the N-terminal region of human ERBB2.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04626 (UniProt, ExPASy)
UniProt Secondary AC B2RZG3, B4DHN3, Q14256, Q6LDV1, Q9UMK4, X5D2V5
UniProt Entry Name ERBB2_HUMAN
NCBI Accession NP_001005862.1 NP_004439.2
KEGG hsa:2064
String 9606.ENSP00000269571
Molecular Weight Calculated MW: 138 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Rat ERBB2.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2)
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