+44 (0) 1223 755950
+1 832 327 7413
Mitogen-Activated Protein Kinase 1 / ERK2 (MAPK1) Antibody
REQUEST MORE INFO
Catalogue No: abx010745
Price:
US$420.50
(Size: 100 µl)
Reviews: 
(1 Publications and Reviews)
(1 Publications and Reviews)
Click on the image to see the image legend
ERK2 (also designated extracellular-signal-related kinase 2 or mitogen-activated protein kinase 1), with 360-amino acid protein (about 40kDa), belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.
Research Articles on Mitogen-Activated Protein Kinase 1 / ERK2 (MAPK1)
| Target | Mitogen-Activated Protein Kinase 1 / ERK2 (MAPK1) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Monkey |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human ERK2 expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P28482 (UniProt, ExPASy) |
| UniProt Secondary AC | A8CZ64 |
| UniProt Entry Name | MK01_HUMAN |
| GeneID | 5594 |
| KEGG | hsa:5594 |
| String | 9606.ENSP00000215832 |
| Molecular Weight | 41 kDa |
| Buffer | PBS, containing 0.03% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |