Mitogen-Activated Protein Kinase 6 / ERK3 (MAPK6) Antibody

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases).MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals.This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain.Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Target	Mitogen-Activated Protein Kinase 6 / ERK3 (MAPK6)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human ERK3 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16659 (UniProt, ExPASy)
UniProt Secondary AC	B2R945, B5BU65, Q68DH4, Q8IYN8
UniProt Entry Name	MK06_HUMAN
Gene Symbol	MAPK6
GeneID	5597
OMIM	602904
HGNC	6879
KEGG	hsa:5597
Ensembl	ENSG00000069956
String	9606.ENSP00000261845
Molecular Weight	105 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitogen-Activated Protein Kinase 6 / ERK3 (MAPK6)

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