+44 (0) 1223 755950
+1 832 327 7413
Mitogen-Activated Protein Kinase 4 / ERK4 (MAPK4) Antibody
REQUEST MORE INFO
Catalogue No: abx033439
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.
Research Articles on Mitogen-Activated Protein Kinase 4 / ERK4 (MAPK4)
| Target | Mitogen-Activated Protein Kinase 4 / ERK4 (MAPK4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 527-557 amino acids from the C-terminal region of human ERK4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by saturated ammonium sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P31152 (UniProt, ExPASy) |
| UniProt Secondary AC | A1A4C4, Q0VG04 |
| Gene Symbol | MAPK4 |
| GeneID | 5596 |
| Molecular Weight | Calculated MW: 65.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |