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ESPL1 (pS1126) Antibody
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Catalogue No: abx000516
Price:
US$232.00
(Size: 20 µl)
Orders to United States ship from United States
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ESPL1 (pS1126) Antibody is a Rabbit Polyclonal antibody against ESPL1 (pS1126). Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids.
Research Articles on ESPL1 (pS1126)
| Target | ESPL1 (pS1126) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around S1126 of human ESPL1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14674 (UniProt, ExPASy) |
| UniProt Entry Name | ESPL1_HUMAN |
| Gene Symbol | ESPL1 |
| GeneID | 9700 |
| NCBI Accession | NP_036423.4 |
| KEGG | hsa:9700 |
| String | 9606.ENSP00000257934 |
| Molecular Weight | Calculated MW: 233 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |