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ETS Translocation Variant 6 (ETV6) Antibody
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Catalogue No: abx001379
Price:
US$203.00
(Size: 20 µl)
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ETV6 Antibody is a Rabbit Polyclonal antibody against ETV6. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008].
Research Articles on ETS Translocation Variant 6 (ETV6)
| Target | ETS Translocation Variant 6 (ETV6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P41212 (UniProt, ExPASy) |
| UniProt Secondary AC | A3QVP6, A8K076, Q9UMF6, Q9UMF7, Q9UMG0 |
| UniProt Entry Name | ETV6_HUMAN |
| Gene Symbol | ETV6 |
| GeneID | 2120 |
| NCBI Accession | NP_001978.1 |
| KEGG | hsa:2120 |
| String | 9606.ENSP00000379658 |
| Molecular Weight | Calculated MW: 53 kDa Observed MW: 53 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |