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Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody
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Catalogue No: abx010312
Price:
US$406.00
(Size: 100 µg)
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Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody is a Rabbit Polyclonal antibody for the detection of 4EBP1. Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Research Articles on Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1)
| Target | Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | eukaryotic translation initiation factor 4E binding protein 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q13541 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R502, D3DSW8, Q6IBN3 |
| UniProt Entry Name | 4EBP1_HUMAN |
| Gene Symbol | EIF4EBP1 |
| GeneID | 1978 |
| OMIM | 602223 |
| HGNC | 3288 |
| KEGG | hsa:1978 |
| Ensembl | ENSG00000187840 |
| String | 9606.ENSP00000340691 |
| Molecular Weight | Observed MW: 17 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |