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Fatty Acid-Binding Protein 4, Adipocyte (FABP4) Antibody
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Catalogue No: abx015746
Price:
US$420.50
(Size: 100 µl)
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Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm.It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism.FABP4 encodes the fatty acid binding protein found in adipocytes.FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.
Research Articles on Fatty Acid-Binding Protein 4, Adipocyte (FABP4)
| Target | Fatty Acid-Binding Protein 4, Adipocyte (FABP4) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of FABP4 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P15090 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6IBA1 |
| UniProt Entry Name | FABP4_HUMAN |
| Gene Symbol | FABP4 |
| GeneID | 2167 |
| OMIM | 600434 |
| HGNC | 3559 |
| KEGG | hsa:2167 |
| Ensembl | ENSG00000170323 |
| String | 9606.ENSP00000256104 |
| Molecular Weight | 14 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |