Fatty Acid-Binding Protein 4, Adipocyte (FABP4) Antibody

Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm.It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism.FABP4 encodes the fatty acid binding protein found in adipocytes.FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.

Target	Fatty Acid-Binding Protein 4, Adipocyte (FABP4)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of FABP4 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P15090 (UniProt, ExPASy)
UniProt Secondary AC	Q6IBA1
UniProt Entry Name	FABP4_HUMAN
Gene Symbol	FABP4
GeneID	2167
OMIM	600434
HGNC	3559
KEGG	hsa:2167
Ensembl	ENSG00000170323
String	9606.ENSP00000256104
Molecular Weight	14 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fatty Acid-Binding Protein 4, Adipocyte (FABP4)

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