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Fanconi Anemia Complementation Group C (FANCC) Antibody
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Catalogue No: abx034404
Price:
US$326.25
(Size: 80 µl)
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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, Fanconi Anemia Group C Protein (FANCC), FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This protein is for complementation group C.
Research Articles on Fanconi Anemia Complementation Group C (FANCC)
| Target | Fanconi Anemia Complementation Group C (FANCC) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/25, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 527-555 amino acids from the C-terminal region of human FANCC. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q00597 (UniProt, ExPASy) |
| UniProt Secondary AC | B1ALR8 |
| UniProt Entry Name | FANCC_HUMAN |
| KEGG | hsa:2176 |
| String | 9606.ENSP00000289081 |
| Molecular Weight | Calculated MW: 63.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |