Prolyl Endopeptidase FAP (FAP) Antibody

Prolyl Endopeptidase FAP (FAP) Antibody is a Rabbit Polyclonal antibody against Prolyl Endopeptidase FAP (FAP). The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Prolyl Endopeptidase FAP (FAP)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	IF/ICC
Host	Rabbit
Recommended dilutions	IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 26-760 of human Fibroblast activation protein-α (FAP).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q12884 (UniProt, ExPASy)
UniProt Secondary AC	O00199, Q53TP5, Q86Z29, Q99998, Q9UID4
Gene Symbol	FAP
GeneID	2191
NCBI Accession	NP_004451.2
Molecular Weight	Calculated MW: 88 kDa Observed MW: 90 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Prolyl Endopeptidase FAP (FAP)

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